CHOP/ORP150 Ratio in Endoplasmic Reticulum Stress: A New Mechanism for Diabetic Peripheral Neuropathy

CHOP/ORP150 Ratio in Endoplasmic Reticulum Stress: A New Mechanism for Diabetic Peripheral Neuropathy

Background/Aims: Peripheral neuropathy is a frequent and severe diabetic complication characterized by progressive loss of peripheral nerve axons and manifested by pain and eventually complete loss of sensation. Effective therapy for diabetic peripheral neuropathy (DPN) is still lacking due to our l...

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Bibliographic Details
Main Authors: Yuan-Bo Wu, Hong-Qi Li, Ming-Shan Ren, Wen-Ting Li, Xin-Yi Lv, Li Wang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Reactive oxygen species (ROS)
Apoptosis
Schwann cells (SCs)
ER stress
CHOP
Diabetic peripheral neuropathy (DPN)
ORP150
Type II diabetes mellitus
Online Access:http://www.karger.com/Article/FullText/354444

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http://www.karger.com/Article/FullText/354444

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