Effects of cessation of cigarette smoking on eicosanoid biomarkers of inflammation and oxidative damage.

The urinary metabolites "prostaglandin E2 metabolite" (PGE-M) and (Z)-7-[1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoic acid (8-iso-PGF2α) are biomarkers of inflammation and oxidative damage, respectively, and are elevated in cigarette smokers. Relatively...

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Bibliographic Details
Main Authors: Joseph P McElroy, Steven G Carmella, Alisa K Heskin, Mei Kuen Tang, Sharon E Murphy, Sarah A Reisinger, Joni A Jensen, Dorothy K Hatsukami, Stephen S Hecht, Peter G Shields
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0218386