Label-free delineation of brain tumors by coherent anti-Stokes Raman scattering microscopy in an orthotopic mouse model and human glioblastoma.

Coherent anti-Stokes Raman scattering (CARS) microscopy provides fine resolution imaging and displays morphochemical properties of unstained tissue. Here, we evaluated this technique to delineate and identify brain tumors.Different human tumors (glioblastoma, brain metastases of melanoma and breast...

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Bibliographic Details
Main Authors: Ortrud Uckermann, Roberta Galli, Sandra Tamosaityte, Elke Leipnitz, Kathrin D Geiger, Gabriele Schackert, Edmund Koch, Gerald Steiner, Matthias Kirsch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4159970?pdf=render