Effect of hypoxia-inducible factor-1α induction by CoCl<sub>2</sub> on breast cancer cells survival: influence of cytochrome-c and survivin

Effect of hypoxia-inducible factor-1α induction by CoCl<sub>2</sub> on breast cancer cells survival: influence of cytochrome-c and survivin

<p><strong>Background:</strong> Tumor tissue usually became hypoxic due to disruption of oxygen supply. Adaptation response to hypoxia is mediated by transcription factor, hypoxia- inducible factor-1α (HIF-1α). HIF-1α signaling is known to increase the expression of pro-apoptotic p...

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Bibliographic Details
Main Authors: Reni Paramita, Mohamad Sadikin, Noorwati Sutandyo, Septelia I. Wanandi
Format: Article
Language:English
Published: Faculty of Medicine Universitas Indonesia 2014-10-01
Series:Medical Journal of Indonesia
Subjects:
apoptosis
cell viability
cytochrome-c
hypoxia-inducible factor-1α
survivin
Online Access:http://mji.ui.ac.id/journal/index.php/mji/article/view/933

Internet

http://mji.ui.ac.id/journal/index.php/mji/article/view/933

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