Frequency of EBV LMP-1 Promoter and Coding Variations in Burkitt Lymphoma Samples in Africa and South America and Peripheral Blood in Uganda

Frequency of EBV LMP-1 Promoter and Coding Variations in Burkitt Lymphoma Samples in Africa and South America and Peripheral Blood in Uganda

Epstein-Barr virus (EBV) is linked to several cancers, including endemic Burkitt lymphoma (eBL), but causal variants are unknown. We recently reported novel sequence variants in the LMP-1 gene and promoter in EBV genomes sequenced from 13 of 14 BL biopsies. Alignments of the novel sequence variants...

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Bibliographic Details
Main Authors: Hsiao-Mei Liao, Hebing Liu, Heiyan Lei, Bingjie Li, Pei-Ju Chin, Shien Tsai, Kishor Bhatia, Marina Gutierrez, Sidnei Epelman, Robert J. Biggar, Francis Nkrumah, Janet Neequaye, Martin D. Ogwang, Steven J. Reynolds, Shyh-Ching Lo, Sam M. Mbulaiteye
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Cancers
Subjects:
Epstein-Barr virus
Burkitt lymphoma
Africa
Latin America
next-generation sequencing
LMP-1
Online Access:http://www.mdpi.com/2072-6694/10/6/177

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http://www.mdpi.com/2072-6694/10/6/177

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