Synthesis and α-Glucosidase Inhibition Activity of 2-[3-(Benzoyl/4-bromobenzoyl)-4-hydroxy-1,1-dioxido-2<i>H</i>-benzo[<i>e</i>][1,2]thiazin-2-yl]-<i>N</i>-arylacetamides: An In Silico and Biochemical Approach

Synthesis and α-Glucosidase Inhibition Activity of 2-[3-(Benzoyl/4-bromobenzoyl)-4-hydroxy-1,1-dioxido-2<i>H</i>-benzo[<i>e</i>][1,2]thiazin-2-yl]-<i>N</i>-arylacetamides: An In Silico and Biochemical Approach

Diabetes mellitus (DM) is a chronic disorder and has affected a large number of people worldwide. Insufficient insulin production causes an increase in blood glucose level that results in DM. To lower the blood glucose level, various drugs are employed that block the activity of the α-glucosidase en...

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Bibliographic Details
Main Authors: Furqan Ahmad Saddique, Sana Aslam, Matloob Ahmad, Usman Ali Ashfaq, Muhammad Muddassar, Sadia Sultan, Saman Taj, Muzammil Hussain, Dae Sung Lee, Magdi E. A. Zaki
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
1,2-Benzothiazines
synthesis
molecular docking
α-glucosidase inhibition
anti-diabetic
Online Access:https://www.mdpi.com/1420-3049/26/10/3043

Internet

https://www.mdpi.com/1420-3049/26/10/3043

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