Insertion of [1.1.1]propellane into aromatic disulfides

Herein we present the synthesis of symmetrically and unsymmetrically substituted 1,3-bissulfanylbicyclo[1.1.1]pentanes from disulfides and [1.1.1]propellane. Bicyclo[1.1.1]pentanes (BCPs) recently gained interest as rigid linkers and as bioisosters of para-substituted benzene and alkyne moieties. Th...

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Bibliographic Details
Main Authors: Robin M. Bär, Gregor Heinrich, Martin Nieger, Olaf Fuhr, Stefan Bräse
Format: Article
Language:English
Published: Beilstein-Institut 2019-05-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.15.114