Efficacy of cotrimoxazole (Sulfamethoxazole-Trimethoprim) as a salvage therapy for the treatment of bone and joint infections (BJIs).

Efficacy of cotrimoxazole (Sulfamethoxazole-Trimethoprim) as a salvage therapy for the treatment of bone and joint infections (BJIs).

INTRODUCTION:Cotrimoxazole (Sulfamethoxazole-Trimethoprim, SXT) has interesting characteristics for the treatment of bone and joint infection (BJI): a broad spectrum of activity with adequate bone diffusion and oral and intravenous formulations. However, its efficacy and safety in BJIs are poorly do...

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Bibliographic Details
Main Authors: Laurene Deconinck, Aurélien Dinh, Christophe Nich, Thomas Tritz, Morgan Matt, Olivia Senard, Simon Bessis, Thomas Bauer, Martin Rottman, Jérome Salomon, Frédérique Bouchand, Benjamin Davido
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0224106

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https://doi.org/10.1371/journal.pone.0224106

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