VASC: Dimension Reduction and Visualization of Single-cell RNA-seq Data by Deep Variational Autoencoder

Single-cell RNA sequencing (scRNA-seq) is a powerful technique to analyze the transcriptomic heterogeneities at the single cell level. It is an important step for studying cell sub-populations and lineages, with an effective low-dimensional representation and visualization of the original scRNA-Seq...

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Bibliographic Details
Main Authors: Dongfang Wang, Jin Gu
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Genomics, Proteomics & Bioinformatics
Online Access:http://www.sciencedirect.com/science/article/pii/S167202291830439X