Integrated epigenomic profiling reveals endogenous retrovirus reactivation in renal cell carcinomaReseach in context

Integrated epigenomic profiling reveals endogenous retrovirus reactivation in renal cell carcinomaReseach in context

Background: Transcriptional dysregulation drives cancer formation but the underlying mechanisms are still poorly understood. Renal cell carcinoma (RCC) is the most common malignant kidney tumor which canonically activates the hypoxia-inducible transcription factor (HIF) pathway. Despite intensive st...

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Bibliographic Details
Main Authors: Kyle T. Siebenthall, Chris P. Miller, Jeff D. Vierstra, Julie Mathieu, Maria Tretiakova, Alex Reynolds, Richard Sandstrom, Eric Rynes, Eric Haugen, Audra Johnson, Jemma Nelson, Daniel Bates, Morgan Diegel, Douglass Dunn, Mark Frerker, Michael Buckley, Rajinder Kaul, Ying Zheng, Jonathan Himmelfarb, Hannele Ruohola-Baker, Shreeram Akilesh
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419300696

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http://www.sciencedirect.com/science/article/pii/S2352396419300696

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