Placental expression of miR-517a/b and miR-517c contributes to trophoblast dysfunction and preeclampsia.

Preeclampsia is a pregnancy specific hypertensive disease that confers significant maternal and fetal risks. While the exact pathophysiology of preeclampsia is unknown, it is widely accepted that placental dysfunction is mechanistically involved. Recent studies reported aberrant expression of placen...

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Bibliographic Details
Main Authors: Lauren Anton, Anthony O Olarerin-George, John B Hogenesch, Michal A Elovitz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0122707