Co-expression Patterns between ATN1 and ATXN2 Coincide with Brain Regions Affected in Huntington’s Disease

Co-expression Patterns between ATN1 and ATXN2 Coincide with Brain Regions Affected in Huntington’s Disease

Cytosine-adenine-guanine (CAG) repeat expansions in the coding regions of nine polyglutamine (polyQ) genes (HTT, ATXN1, ATXN2, ATXN3, CACNA1A, ATXN7, ATN1, AR, and TBP) are the cause of several neurodegenerative diseases including Huntington’s disease (HD), six different spinocerebellar ataxias (SCA...

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Bibliographic Details
Main Authors: Arlin Keo, N. Ahmad Aziz, Oleh Dzyubachyk, Jeroen van der Grond, Willeke M. C. van Roon-Mom, Boudewijn P. F. Lelieveldt, Marcel J. T. Reinders, Ahmed Mahfouz
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
gene co-expression
polyglutamine diseases
human brain
Huntington’s disease
neurodegeneration
MRI
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00399/full

Internet

http://journal.frontiersin.org/article/10.3389/fnmol.2017.00399/full

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