Natural Selection of H5N1 Avian Influenza A Viruses with Increased PA-X and NS1 Shutoff Activity

Influenza A viruses (IAV) can infect a broad range of mammalian and avian species. However, the host innate immune system provides defenses that restrict IAV replication and infection. Likewise, IAV have evolved to develop efficient mechanisms to counteract host antiviral responses to efficiently re...

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Bibliographic Details
Main Authors: Aitor Nogales, Laura Villamayor, Sergio Utrilla-Trigo, Javier Ortego, Luis Martinez-Sobrido, Marta L. DeDiego
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Viruses
Subjects:
NS1
Online Access:https://www.mdpi.com/1999-4915/13/9/1760