Rhes regulates dopamine D2 receptor transmission in striatal cholinergic interneurons

Rhes regulates dopamine D2 receptor transmission in striatal cholinergic interneurons

Ras homolog enriched in striatum (Rhes) is highly expressed in striatal medium spiny neurons (MSNs) of rodents. In the present study, we characterized the expression of Rhes mRNA across species, as well as its functional role in other striatal neuron subtypes. Double in situ hybridization analysis s...

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Bibliographic Details
Main Authors: Giuseppe Sciamanna, Francesco Napolitano, Barbara Pelosi, Paola Bonsi, Daniela Vitucci, Tommaso Nuzzo, Daniela Punzo, Veronica Ghiglieri, Giulia Ponterio, Massimo Pasqualetti, Antonio Pisani, Alessandro Usiello
Format: Article
Language:English
Published: Elsevier 2015-06-01
Series:Neurobiology of Disease
Subjects:
Rhes
Striatum
Cholinergic interneurons
D2 dopamine receptors
Calcium
Dystonia
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996115000935

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http://www.sciencedirect.com/science/article/pii/S0969996115000935

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