Plasticiser-Free 3D Printed Hydrophilic Matrices: Quantitative 3D Surface Texture, Mechanical, Swelling, Erosion, Drug Release and Pharmacokinetic Studies

Plasticiser-Free 3D Printed Hydrophilic Matrices: Quantitative 3D Surface Texture, Mechanical, Swelling, Erosion, Drug Release and Pharmacokinetic Studies

Hydroxypropyl methyl cellulose, HPMC, a hydrophilic polymer, is widely used for the development of extended release hydrophilic matrices and it is also considered as a good contender for the fabrication of 3D printing of matrix tablets. It is often combined with plasticisers to enable extrusion. The...

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Bibliographic Details
Main Authors: Zara Khizer, Muhammad R. Akram, Rai M. Sarfraz, Jorabar Singh Nirwan, Samia Farhaj, Maria Yousaf, Tariq Hussain, Shan Lou, Peter Timmins, Barbara R. Conway, Muhammad Usman Ghori
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Polymers
Subjects:
3D printing
hot melt extrusion
hydroxypropyl methyl cellulose (HPMC)
swelling
erosion
drug release
pharmacokinetics
Young’s modulus
3D surface texture
Online Access:https://www.mdpi.com/2073-4360/11/7/1095

Internet

https://www.mdpi.com/2073-4360/11/7/1095

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