Therapeutic vaccination of SIV-infected, ART-treated infant rhesus macaques using Ad48/MVA in combination with TLR-7 stimulation.

Therapeutic vaccination of SIV-infected, ART-treated infant rhesus macaques using Ad48/MVA in combination with TLR-7 stimulation.

Globally, 1.8 million children are living with HIV-1. While antiretroviral therapy (ART) has improved disease outcomes, it does not eliminate the latent HIV-1 reservoir. Interventions to delay or prevent viral rebound in the absence of ART would be highly beneficial for HIV-1-infected children who n...

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Bibliographic Details
Main Authors: Katherine M Bricker, Veronica Obregon-Perko, Ferzan Uddin, Brianna Williams, Emilie A Uffman, Carolina Garrido, Genevieve G Fouda, Romas Geleziunas, Merlin Robb, Nelson Michael, Dan H Barouch, Ann Chahroudi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008954

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https://doi.org/10.1371/journal.ppat.1008954

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