Network-centric medicine for peripheral nerve injury: Treating the whole to boost endogenous mechanisms of neuroprotection and regeneration

Network-centric medicine for peripheral nerve injury: Treating the whole to boost endogenous mechanisms of neuroprotection and regeneration

Peripheral nerve injuries caused by accidents may lead to paralysis, sensory disturbances, anaesthesia, and lack of autonomic functions. Functional recovery after disconnection of the motoneuronal soma from target tissue with proximal rupture of axons is determined by several factors: motoneuronal s...

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Bibliographic Details
Main Authors: David Romeo-Guitart, Caty Casas
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Neural Regeneration Research
Subjects:
motoneuron; neurodegeneration; axonal regeneration; muscle atrophy; systems biology; neuroheal; PI3K/AKT; sirtuin 1; motor function recovery
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=7;spage=1122;epage=1128;aulast=Romeo-Guitart

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=7;spage=1122;epage=1128;aulast=Romeo-Guitart

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