Plasmid DNA Production in Proteome-Reduced <i>Escherichia coli</i>

The design of optimal cell factories requires engineering resource allocation for maximizing product synthesis. A recently developed method to maximize the saving in cell resources released 0.5% of the proteome of <i>Escherichia coli</i> by deleting only three transcription factors. We a...

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Bibliographic Details
Main Authors: Mitzi de la Cruz, Elisa A. Ramírez, Juan-Carlos Sigala, José Utrilla, Alvaro R. Lara
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Microorganisms
Subjects:
Online Access:https://www.mdpi.com/2076-2607/8/9/1444