Inhibitory effect of panaxytriol on BV-2 microglial cell activation

Inhibitory effect of panaxytriol on BV-2 microglial cell activation

Activated microglia induce brain inflammation and neuronal death. Panaxytriol, ((3R,9R,10R)-Heptadec-1-en-4,6-diyne-3,9,10-triol), is a component of Panax ginseng C. A. Meyer extracts and activates the Nrf2-ARE signaling pathway. However, little is known about its effects on activated microglia in t...

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Bibliographic Details
Main Authors: Genki Hiramatsu, Daisuke Uta, Kenichi Mihara, Tsugunobu Andoh, Toshiaki Kume
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Journal of Pharmacological Sciences
Subjects:
Microglia activation
Panaxytriol
NF-κB
Brain inflammation
Antiinflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861321000025

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http://www.sciencedirect.com/science/article/pii/S1347861321000025

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