Leukemia Inhibitory Factor Induces Proopiomelanocortin via CRH/CRHR Pathway in Mouse Trophoblast

Leukemia Inhibitory Factor Induces Proopiomelanocortin via CRH/CRHR Pathway in Mouse Trophoblast

We previously showed that maternal leukemia inhibitory factor (LIF) induces placental production of adrenocorticotropic hormone (ACTH), which stimulates fetal nucleated red blood cells to further secrete LIF and promote neurogenesis in rodent brains. However, the underlying mechanism of LIF-dependen...

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Bibliographic Details
Main Authors: He Wang, Hiromi Sakata-Haga, Hiroko Masuta, Mitsuhiro Tomosugi, Tsuyoshi Tsukada, Hiroki Shimada, Daisuke Sakai, Hiroki Shoji, Toshihisa Hatta
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
leukemia inhibitory factor
corticotropin-releasing hormone
corticotropin-releasing hormone receptor
proopiomelanocortin
mouse trophoblast stem cells
mouse placenta
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.618947/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.618947/full

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