Effects of FGFR gene polymorphisms on response and toxicity of cyclophosphamide-epirubicin-docetaxel-based chemotherapy in breast cancer patients

Effects of FGFR gene polymorphisms on response and toxicity of cyclophosphamide-epirubicin-docetaxel-based chemotherapy in breast cancer patients

Abstract Background The chemotherapy resistance and toxicity of chemotherapy are major problems in breast cancer treatment. However, candidate biomarkers for predicting clinical outcomes and better prognosis remain lacking. Methods In this study, we analyzed possible impact of 8 genetic variants of...

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Bibliographic Details
Main Authors: Lu Chen, Huijie Qi, Liudi Zhang, Haixia Li, Jie Shao, Haifei Chen, Mingkang Zhong, Xiaojin Shi, Ting Ye, Qunyi Li
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Cancer
Subjects:
Fibroblast growth factor receptors
rs1966265
rs2981578
Single-nucleotide polymorphism
Neoadjuvant chemotherapy
Breast cancer
Online Access:http://link.springer.com/article/10.1186/s12885-018-4951-z

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http://link.springer.com/article/10.1186/s12885-018-4951-z

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