Tumor-intrinsic signaling pathways: key roles in the regulation of the immunosuppressive tumor microenvironment

Tumor-intrinsic signaling pathways: key roles in the regulation of the immunosuppressive tumor microenvironment

Abstract Immunotherapy is a currently popular treatment strategy for cancer patients. Although recent developments in cancer immunotherapy have had significant clinical impact, only a subset of patients exhibits clinical response. Therefore, understanding the molecular mechanisms of immunotherapy re...

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Bibliographic Details
Main Authors: Li Yang, Aitian Li, Qingyang Lei, Yi Zhang
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Hematology & Oncology
Subjects:
Immunosuppressive tumor microenvironment
Immune escape
T cell infiltration
Immunosuppressive cells
Tumor-intrinsic signaling
Online Access:http://link.springer.com/article/10.1186/s13045-019-0804-8

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http://link.springer.com/article/10.1186/s13045-019-0804-8

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