Comprehensive FISH probe design tool applied to imaging human immunoglobulin class switch recombination.

We present a web engine boosted fluorescence in-situ hybridization (webFISH) algorithm using a genome-wide sequence similarity search to design target-specific single-copy and repetitive DNA FISH probes. The webFISH algorithm featuring a user-friendly interface (http://www.webfish2.org/) maximizes t...

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Bibliographic Details
Main Authors: Jakub Nedbal, Philip S Hobson, David J Fear, Rainer Heintzmann, Hannah J Gould
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3522715?pdf=render