Preparation, Characterization, and In Vivo Evaluation of Amorphous Icaritin Nanoparticles Prepared by a Reactive Precipitation Technique

Preparation, Characterization, and In Vivo Evaluation of Amorphous Icaritin Nanoparticles Prepared by a Reactive Precipitation Technique

Icaritin is a promising anti-hepatoma drug that is currently being tested in a phase-III clinical trial. A novel combination of amorphization and nanonization was used to enhance the oral bioavailability of icaritin. Amorphous icaritin nanoparticles (AINs) were prepared by a reactive precipitation t...

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Bibliographic Details
Main Authors: Cheng Tang, Kun Meng, Xiaoming Chen, Hua Yao, Junqiong Kong, Fusu Li, Haiyan Yin, Mingji Jin, Hao Liang, Qipeng Yuan
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
icaritin
anti-hepatoma drug
flavonoids
amorphous nanoparticles
reactive precipitation technique
Online Access:https://www.mdpi.com/1420-3049/26/10/2913

Internet

https://www.mdpi.com/1420-3049/26/10/2913

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