Potential Utility of Biased GPCR Signaling for Treatment of Psychiatric Disorders

Potential Utility of Biased GPCR Signaling for Treatment of Psychiatric Disorders

Tremendous advances have been made recently in the identification of genes and signaling pathways associated with the risks for psychiatric disorders such as schizophrenia and bipolar disorder. However, there has been a marked reduction in the pipeline for the development of new psychiatric drugs wo...

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Bibliographic Details
Main Authors: Hidetoshi Komatsu, Mamoru Fukuchi, Yugo Habata
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:International Journal of Molecular Sciences
Subjects:
GPCR
biased ligand
dopamine D2 receptor
aripiprazole
quetiapine
β-arrestin
psychiatric disorder
schizophrenia
bipolar disorder
Online Access:https://www.mdpi.com/1422-0067/20/13/3207

Internet

https://www.mdpi.com/1422-0067/20/13/3207

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