Cell-Free Glycoengineering of the Recombinant SARS-CoV-2 Spike Glycoprotein

The baculovirus-insect cell expression system is readily utilized to produce viral glycoproteins for research as well as for subunit vaccines and vaccine candidates, for instance against SARS-CoV-2 infections. However, the glycoforms of recombinant proteins derived from this expression system are in...

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Bibliographic Details
Main Authors: Johannes Ruhnau, Valerian Grote, Mariana Juarez-Osorio, Dunja Bruder, Reza Mahour, Erdmann Rapp, Thomas F. T. Rexer, Udo Reichl
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.699025/full