JNK Signaling Pathway Suppresses LPS-Mediated Apoptosis of HK-2 Cells by Upregulating NGAL

Objective. To explore the role of the c-Jun N-terminal kinase (JNK) signaling pathway in upregulated NGAL expression and its antiapoptotic mechanism in lipopolysaccharide (LPS)-mediated renal tubular epithelial cell injury. Methods. In vitro, HK-2 cells were divided into five groups (Con, LPS 1 h, L...

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Bibliographic Details
Main Authors: Mei Han, Yuxia Pan, Mengying Gao, Junli Zhang, Fan Wang
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:International Journal of Inflammation
Online Access:http://dx.doi.org/10.1155/2020/3980507