STAT1-dependent and -independent pulmonary allergic and fibrogenic responses in mice after exposure to tangled versus rod-like multi-walled carbon nanotubes

STAT1-dependent and -independent pulmonary allergic and fibrogenic responses in mice after exposure to tangled versus rod-like multi-walled carbon nanotubes

Abstract Background Pulmonary toxicity of multi-walled carbon nanotubes (MWCNTs) is influenced by physicochemical characteristics and genetic susceptibility. We hypothesized that contrasting rigidities of tangled (t) versus rod-like (r) MWCNTs would result in differing immunologic or fibrogenic resp...

Full description

Bibliographic Details
Main Authors: Katherine S. Duke, Alexia J. Taylor-Just, Mark D. Ihrie, Kelly A. Shipkowski, Elizabeth A. Thompson, Erinn C. Dandley, Gregory N. Parsons, James C. Bonner
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Particle and Fibre Toxicology
Subjects:
Carbon nanotubes
Lung
Fibrosis
Growth factors
Transcription factors
Online Access:http://link.springer.com/article/10.1186/s12989-017-0207-3

Internet

http://link.springer.com/article/10.1186/s12989-017-0207-3

Similar Items