eXtraembryonic ENdoderm (XEN) stem cells produce factors that activate heart formation.

Initial specification of cardiomyocytes in the mouse results from interactions between the extraembryonic anterior visceral endoderm (AVE) and the nascent mesoderm. However the mechanism by which AVE activates cardiogenesis is not well understood, and the identity of specific cardiogenic factors in...

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Bibliographic Details
Main Authors: Kemar Brown, Michael Xavier Doss, Stephanie Legros, Jérôme Artus, Anna-Katerina Hadjantonakis, Ann C Foley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2958120?pdf=render