Beneficial effects of ascorbic acid to treat lung fibrosis induced by paraquat.

Paraquat (PQ) is one of the most widely employed herbicides that is used worldwide and it causes severe toxic effects in humans and animals. A PQ exposition can lead to pulmonary fibrosis (PF) and the mechanisms seem to be linked to oxidative stress, although other pathways have been suggested. Anti...

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Main Authors: Marcia Rodrigues da Silva, Adriana Schapochnik, Mayara Peres Leal, Janete Esteves, Cristina Bichels Hebeda, Silvana Sandri, Christiane Pavani, Anna Carolina Ratto Tempestini Horliana, Sandra H P Farsky, Adriana Lino-Dos-Santos-Franco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6218022?pdf=render