TCF7L2 regulates pancreatic β-cell function through PI3K/AKT signal pathway
Abstract Background Transcription factor 7-like 2 (TCF7L2), which previously known as TCF-4, is a major form of transcription factor involved in the downstream WNT signaling and exhibits the strongest association to diabetes susceptibility. Although we still do not know mechanistically how TCF7L2 ex...
Main Authors: | Hui-Hui Wu, Yan-Liang Li, Nai-Jia Liu, Zhen Yang, Xiao-Ming Tao, Yan-Ping Du, Xuan-Chun Wang, Bin Lu, Zhao-Yun Zhang, Ren-Ming Hu, Jie Wen |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-07-01
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Series: | Diabetology & Metabolic Syndrome |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13098-019-0449-3 |
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