Life-Threatening Gastrointestinal Mucosal Necrosis during Methotrexate Treatment for Rheumatoid Arthritis

Life-Threatening Gastrointestinal Mucosal Necrosis during Methotrexate Treatment for Rheumatoid Arthritis

Methotrexate (MTX), a folic acid antagonist, is widely used in the treatment of neoplasms, psoriasis and rheumatoid arthritis. Despite its efficacy, MTX sometimes finds limited application because of its adverse effects, including renal or liver impairment, bone marrow toxicity and gastrointestinal...

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Bibliographic Details
Main Authors: Tomoya Tsukada, Tatsuo Nakano, Takashi Miyata, Shozo Sasaki
Format: Article
Language:English
Published: Karger Publishers 2013-11-01
Series:Case Reports in Gastroenterology
Subjects:
Methotrexate
Adverse effect
Drug lymphocyte stimulation test
Type IV allergic reactions
Gastrointestinal tract
Mucosal injury
Necrosis
Rheumatoid arthritis
Online Access:http://www.karger.com/Article/FullText/356817

Internet

http://www.karger.com/Article/FullText/356817

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