Concurrent expression of HP-NAP enhances antitumor efficacy of oncolytic vaccinia virus but not for Semliki Forest virus

Oncolytic viruses (OVs) represent promising therapeutic agents for cancer therapy by selective oncolysis and induction of anti-tumor immunity. OVs can be engineered to express tumor-associated antigens and immune-modulating agents to provoke stronger antitumor immunity. Here, we engineered vaccinia...

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Bibliographic Details
Main Authors: Jing Ma, Chuan Jin, Matko Čančer, Hai Wang, Mohanraj Ramachandran, Di Yu
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Molecular Therapy: Oncolytics
Subjects:
NAP
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770521000668