MicroRNA-153 Regulates the Acquisition of Gliogenic Competence by Neural Stem Cells

MicroRNA-153 Regulates the Acquisition of Gliogenic Competence by Neural Stem Cells

Mammalian neural stem/progenitor cells (NSPCs) sequentially generate neurons and glia during CNS development. Here we identified miRNA-153 (miR-153) as a modulator of the temporal regulation of NSPC differentiation. Overexpression (OE) of miR-153 delayed the onset of astrogliogenesis and maintained...

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Bibliographic Details
Main Authors: Jun Tsuyama, Jens Bunt, Linda J. Richards, Hiroko Iwanari, Yasuhiro Mochizuki, Takao Hamakubo, Takuya Shimazaki, Hideyuki Okano
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115001873

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http://www.sciencedirect.com/science/article/pii/S2213671115001873

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