Digital Gene Expression Analysis of Epithelioid and Sarcomatoid Mesothelioma Reveals Differences in Immunogenicity

Digital Gene Expression Analysis of Epithelioid and Sarcomatoid Mesothelioma Reveals Differences in Immunogenicity

Malignant pleural mesothelioma (MPM) is an aggressive malignancy associated with asbestos exposure. Median survival ranges from 14 to 20 months after initial diagnosis. As of November 2020, the FDA approved a combination of immune checkpoint inhibitors after promising intermediate results. Nonethele...

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Bibliographic Details
Main Authors: Luka Brcic, Alexander Mathilakathu, Robert F. H. Walter, Michael Wessolly, Elena Mairinger, Hendrik Beckert, Daniel Kreidt, Julia Steinborn, Thomas Hager, Daniel C. Christoph, Jens Kollmeier, Thomas Mairinger, Jeremias Wohlschlaeger, Kurt Werner Schmid, Sabrina Borchert, Fabian D. Mairinger
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
pleural mesothelioma
gene expression
immunogenicity
sarcomatoid
epithelioid
Online Access:https://www.mdpi.com/2072-6694/13/8/1761

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https://www.mdpi.com/2072-6694/13/8/1761

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