Screening of drugs to treat 8p11 myeloproliferative syndrome using patient-derived induced pluripotent stem cells with fusion gene CEP110-FGFR1.

Screening of drugs to treat 8p11 myeloproliferative syndrome using patient-derived induced pluripotent stem cells with fusion gene CEP110-FGFR1.

Induced pluripotent stem (iPS) cells provide powerful tools for studying disease mechanisms and developing therapies for diseases. The 8p11 myeloproliferative syndrome (EMS) is an aggressive chronic myeloproliferative disorder (MPD) that is caused by constitutive activation of fibroblast growth fact...

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Bibliographic Details
Main Authors: Shohei Yamamoto, Makoto Otsu, Emiko Matsuzaka, Chieko Konishi, Haruna Takagi, Sachiyo Hanada, Shinji Mochizuki, Hiromitsu Nakauchi, Kohzoh Imai, Kohichiro Tsuji, Yasuhiro Ebihara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4372437?pdf=render

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http://europepmc.org/articles/PMC4372437?pdf=render

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