Recognizing and stabilizing miR-21 by chiral ruthenium(II) complexes

Abstract MiR-21, a non-coding miRNA with 22 nucleotides, plays an important part in the proliferation, invasion, and metastasis of tumor cells. The present study demonstrates that isomers of chiral ruthenium(II) complexes with alkynes (Λ-1 and Δ-1) were synthesized by Songogashira coupling reaction...

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Bibliographic Details
Main Authors: Yin Feng, Jing Shu, Liangzhong Yao, Yutao Lan, Lianbao Ye, Wenjie Mei, Ying Ding
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Chemistry
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13065-020-00672-8