Treatment and secondary prophylaxis of venous thromboembolism with direct oral anticoagulants in patients with severe hereditary thrombophilia

Deficiency of protein C (PC), protein S (PS), antithrombin III (AT III), and homozygosity or combined heterozygosity for Factor V Leiden (FVL) and Factor II (FII) 20210A mutation represent severe hereditary thrombophilia (SHT) and are associated with a higher risk of early-onset venous thromboembol...

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Bibliographic Details
Main Authors: Pasquale Madonna, Anna Guida, Maria Gabriella Coppola, Paolo Tirelli, Ernesto Grasso
Format: Article
Language:English
Published: PAGEPress Publications 2021-03-01
Series:Italian Journal of Medicine
Subjects:
Online Access:https://italjmed.org/index.php/ijm/article/view/1351