Inflammatory stimuli reprogram macrophage phagocytosis to macropinocytosis for the rapid elimination of pathogens.

Following an infectious challenge, macrophages have to be activated in order to allow efficient clearance of infectious pathogens, but how macrophage activation is coupled to increased clearance remains largely unknown. We here describe that inflammatory stimuli induced the reprogramming of the macr...

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Bibliographic Details
Main Authors: Somdeb Bosedasgupta, Jean Pieters
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3907376?pdf=render