PPAR-δ agonist affects adipo-chondrogenic differentiation of human mesenchymal stem cells through the expression of PPAR-γ

PPAR-δ agonist affects adipo-chondrogenic differentiation of human mesenchymal stem cells through the expression of PPAR-γ

Introduction: Peroxisome proliferator–activated receptor (PPAR) subfamily play an important role in chondrogenesis. Previous study has reported that mixture of GW0742 (PPAR-δ agonist), hyaluronic acid (HA) and mesenchymal stem cells (MSCs) enhance chondrogenesis. The purpose of this study is to comp...

Full description

Bibliographic Details
Main Authors: Dong Hyun Kim, Dong Hwan Kim, Bruce E. Heck, Michael Shaffer, Keon Hee Yoo, Jin Hur
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Regenerative Therapy
Subjects:
Mesenchymal stem cells
PPAR-γ
PPAR-δ
Chondrogenesis
Adipogenesis
Type Ⅱ collagen
Online Access:http://www.sciencedirect.com/science/article/pii/S2352320420300584

Internet

http://www.sciencedirect.com/science/article/pii/S2352320420300584

Similar Items