Synthesis and Antiproliferative Activity of C-3 Functionalized Isobenzofuran-1(3H)-ones

Synthesis and Antiproliferative Activity of C-3 Functionalized Isobenzofuran-1(3H)-ones

A series of thirteen C-3 functionalized isobenzofuran-1(3H)-ones (phtalides) was synthesized via condensation, aromatization, and acetylation reactions. NMR (one and two dimensional experiments), IR, and mass spectrometry analysis allowed confirmation of the identity of the synthesized compounds. Th...

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Bibliographic Details
Main Authors: Fabrício Marques de Oliveira, Joana Gasperazzo Ferreira, Wagner Luiz Pereira, Gustavo Costa Bressan, Róbson Ricardo Teixeira, Deborah Campos Thomaz
Format: Article
Language:English
Published: MDPI AG 2013-02-01
Series:Molecules
Subjects:
isobenzofuran-1(3H)-one
phtalides
antiproliferative activity
Online Access:http://www.mdpi.com/1420-3049/18/2/1881

Internet

http://www.mdpi.com/1420-3049/18/2/1881

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