In Silico Screening Anticancer of Six Triterpenoids toward miR-494 and TNF-α Targets

In Silico Screening Anticancer of Six Triterpenoids toward miR-494 and TNF-α Targets

Hepatocellular carcinoma (HCC) accounts for up to 90% of all primary liver cancers worldwide. Cinobufagin is recognized to inhibit miR-494 as the HCC target. Increased expression of TNF-α results in an inadequate response to liver anticancer drugs. The models in this study were cinobufagin, cycloart...

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Bibliographic Details
Main Authors: Vikra Ardiansyah Zaini, Purwantiningsih Sugita, Luthfan Irfana, Suminar Setiati Achmadi
Format: Article
Language:English
Published: Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University 2020-04-01
Series:Jurnal Kimia Sains dan Aplikasi
Subjects:
akt
cycloartenol
ganoderma lucidum
hepatocellular carcinoma
triterpenoids
Online Access:https://ejournal.undip.ac.id/index.php/ksa/article/view/27122

Internet

https://ejournal.undip.ac.id/index.php/ksa/article/view/27122

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