APEX Fingerprinting Reveals the Subcellular Localization of Proteins of Interest

APEX Fingerprinting Reveals the Subcellular Localization of Proteins of Interest

Deciphering the sub-compartmental location of a given protein of interest may help explain its physiological function, but it can be challenging to do using optical or biochemical methods. Imaging with electron microscopy (EM) can provide highly resolved mapping of proteins; however, EM requires com...

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Bibliographic Details
Main Authors: Song-Yi Lee, Myeong-Gyun Kang, Jong-Seok Park, Geunsik Lee, Alice Y. Ting, Hyun-Woo Rhee
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Cell Reports
Subjects:
engineered ascorbate peroxidase
molecular pattern
membrane protein topology
protein localization mapping
proximity labeling
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716305083

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http://www.sciencedirect.com/science/article/pii/S2211124716305083

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