The adenomatous polyposis coli protein contributes to normal compaction of mitotic chromatin.

The adenomatous polyposis coli protein contributes to normal compaction of mitotic chromatin.

The tumour suppressor Adenomatous Polyposis Coli (APC) is required for proper mitosis; however, the exact role of APC in mitosis is not understood. Using demembranated sperm chromatin exposed to meiotic Xenopus egg extract and HeLa cells expressing fluorescently labelled histones, we established tha...

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Bibliographic Details
Main Authors: Dina Dikovskaya, Guennadi Khoudoli, Ian P Newton, Gaganmeet S Chadha, Daniel Klotz, Ashwat Visvanathan, Angus Lamond, Jason R Swedlow, Inke S Näthke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3374815?pdf=render

Internet

http://europepmc.org/articles/PMC3374815?pdf=render

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