Murid herpesvirus-4 exploits dendritic cells to infect B cells.

Murid herpesvirus-4 exploits dendritic cells to infect B cells.

Dendritic cells (DCs) play a central role in initiating immune responses. Some persistent viruses infect DCs and can disrupt their functions in vitro. However, these viruses remain strongly immunogenic in vivo. Thus what role DC infection plays in the pathogenesis of persistent infections is unclear...

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Bibliographic Details
Main Authors: Miguel Gaspar, Janet S May, Soumi Sukla, Bruno Frederico, Michael B Gill, Christopher M Smith, Gabrielle T Belz, Philip G Stevenson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-11-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22102809/pdf/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22102809/pdf/?tool=EBI

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