A comprehensive analysis of the structure-function relationship in proteins based on local structure similarity.
BACKGROUND:Sequence similarity to characterized proteins provides testable functional hypotheses for less than 50% of the proteins identified by genome sequencing projects. With structural genomics it is believed that structural similarities may give functional hypotheses for many of the remaining p...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-07-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2705683?pdf=render |