Mutations in planar cell polarity gene SCRIB are associated with spina bifida.

Mutations in planar cell polarity gene SCRIB are associated with spina bifida.

Neural tube defects (NTDs) (OMIM #182940) including anencephaly, spina bifida and craniorachischisis, are severe congenital malformations that affect 0.5-1 in 1,000 live births in the United States, with varying prevalence around the world. Mutations in planar cell polarity (PCP) genes are believed...

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Bibliographic Details
Main Authors: Yunping Lei, Huiping Zhu, Cody Duhon, Wei Yang, M Elizabeth Ross, Gary M Shaw, Richard H Finnell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3724847?pdf=render

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http://europepmc.org/articles/PMC3724847?pdf=render

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