Immortalized Human hTert/KER-CT Keratinocytes a Model System for Research on Desmosomal Adhesion and Pathogenesis of Pemphigus Vulgaris

Immortalized Human hTert/KER-CT Keratinocytes a Model System for Research on Desmosomal Adhesion and Pathogenesis of Pemphigus Vulgaris

Pemphigus Vulgaris is an autoimmune disease that results in blister formation in the epidermis and in mucosal tissues due to antibodies recognizing desmosomal cadherins, mainly desmoglein-3 and -1. Studies on the molecular mechanisms of Pemphigus have mainly been carried out using the spontaneously...

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Bibliographic Details
Main Authors: Benedikt Beckert, Francesca Panico, Robert Pollmann, Rüdiger Eming, Antje Banning, Ritva Tikkanen
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:International Journal of Molecular Sciences
Subjects:
desmosome
desmoglein
flotillin
cell-cell adhesion
Pemphigus vulgaris
blistering disease
dermatology
epidermis
Online Access:https://www.mdpi.com/1422-0067/20/13/3113

Internet

https://www.mdpi.com/1422-0067/20/13/3113

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