Changes in tau phosphorylation levels in the hippocampus and frontal cortex following chronic stress

Studies have indicated that early-life or early-onset depression is associated with a 2- to 4-fold increased risk of developing Alzheimers disease (AD). In AD, aggregation of an abnormally phosphorylated form of the tau protein may be a key pathological event. Tau is known to play a major role in pr...

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Bibliographic Details
Main Authors: C. Yang, X. Guo, G.H. Wang, H.L. Wang, Z.C. Liu, H. Liu, Z.X. Zhu, Y. Li
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2014-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Tau
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000300237&lng=en&tlng=en