Selective anticancer activity of a hexapeptide with sequence homology to a non-kinase domain of Cyclin Dependent Kinase 4

Selective anticancer activity of a hexapeptide with sequence homology to a non-kinase domain of Cyclin Dependent Kinase 4

<p>Abstract</p> <p>Background</p> <p>Cyclin-dependent kinases 2, 4 and 6 (Cdk2, Cdk4, Cdk6) are closely structurally homologous proteins which are classically understood to control the transition from the G1 to the S-phases of the cell cycle by combining with their appr...

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Bibliographic Details
Main Authors: Agarwala Usha, Blaydes Jeremy P, Maurer Richard I, Essex Jon W, Kilburn Jeremy D, Warenius Hilmar M, Seabra Laurence A
Format: Article
Language:English
Published: BMC 2011-06-01
Series:Molecular Cancer
Subjects:
Cdk4
non-kinase
proteomic
PRGPRP
programmed cell death
selective anticancer
broad spectrum
Online Access:http://www.molecular-cancer.com/content/10/1/72

Internet

http://www.molecular-cancer.com/content/10/1/72

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